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Doripenem Condensation Compound

Structure : Synthesis Route certificate of analysis : ProductName: Doripenem Condensation Compound Cas: 491878-07-0 Batch No.: 20110518 MFG Date: May.18.2011 Analysis Date : May.18.2011

  • Features & Specification

    PRODUCT NAME

    Doripenem Condensation Compound

    CAS No.:

    491878-07-0

    Synonyms

    4-nitrobenzyl (4R,5S,6S)-6-[(1R)-1-hydroxyethyl]-4-methyl-3-[[(3S,5S)-1-(4-nitrobenzyloxycarbonyl)-5-(sulfamoylaminomethyl)pyrrolidin-3-yl]thio]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate

    Formula

    C30H34N6O12S2

    Molecular Weight

    734.75400

    PSA:

    293.89000

    LogP:

    5.01550

    Structure: 

    图片25.png  
    Synthesis Route
     

    图片26.png

    certificate of analysis

    ProductName: Doripenem Condensation Compound
    Cas:       491878-07-0
    Batch No.:  20110518
    MFG Date:  May.18.2011
    Analysis Date: May.18.2011

    Inspect Item

    Quantity Standard

    Inspection Result

    Appearance

    White to off-white crystalline powder

    Conforms

    Assay

    ≥95%

    97.27%

    Melting Point

    88~92℃

    89~91℃

    Loss on drying

    0.5%w/w

    0.47%

    Heavy metals

    10ppm

    Conforms

    Individual impurity

    0.5%

    0.28%

    Total impurity

    5 %

    2.73%

    Conclusion

    In accordance with enterprise standard

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