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4-Dehydroxy-4-dimethylphenylsilyl Entecavir

Structure : Description 4-Dehydroxy-4-dimethylphenylsilyl Entecavir is an impurity of Entecavir. Certificate of Analysis Product Name: 2-Amino-9-[(1S,3R,4S)-4-(dimethylphenylsilyl)-3-(hydroxymethyl) -2-methylenecycl opentyl]-1,9-dihydro-6H-purin-6-one Cas: 701278-07-1 Batch No.: 20100307 MFG...

  • Features & Specification

    PRODUCT NAME

    2-Amino-9-[(1S,3R,4S)-4-(dimethylphenylsilyl)-3(hydroxy

    methyl) -2-methylenecycl opentyl]-1,9-dihydro-6H-purin-6-one

    CAS No.:

    701278-07-1

    Synonyms:

    6H-Purin-6-one,2-amino-9-[(1S,3R,4S)-4-(dimethylphenylsilyl)-3-(hydroxymethyl)-2-methylenecyclopentyl]-1,9-dihydro;

    4-Dehydroxy-4-dimethylphenylsilyl Entecavir;

    Formula:

    C20H25N5O2Si

    Molecular Weight:

    395.53000

    PSA:

    109.82000

    LogP:

    2.37830

     

    Structure

    image.png                              

     

    Description

    Density:

    1.34

    Refractive Index:

    1.672

    4-Dehydroxy-4-dimethylphenylsilyl Entecavir is an impurity of Entecavir.

     

    Certificate of Analysis

     

    Product Name: 2-Amino-9-[(1S,3R,4S)-4-(dimethylphenylsilyl)-3-(hydroxymethyl) -2-methylenecycl opentyl]-1,9-dihydro-6H-purin-6-one

    Cas: 701278-07-1

    Batch No.: 20100307

    MFG Date: Jan. 12.2010

    Analysis Date: Jan. 12.2010

     

    Inspect Item

    Quantity Standard

    Inspection Result

    Appearance

    White to light yellow   powder

    Conforms

    Specific rotation

    +53 ~ +57°

    +55.0~55.5°

    Identification

    IR

    Conforms

    M.P.

    98-103℃

    99-101℃

    Water(K.F.)

    ≤5.0%

    3.0%

    Lead

    ≤0.001%

    Conforms

    Heavy metals

    ≤20ppm

    <20ppm

    Assay

    Not less than 98%

    99.27%

    Conclusion

    Up to enterprise grade

     

     


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