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4-Cloromethyl-5-methyl-1,3-dioxol-2-one

4-Chloromethyl-5-methyl-1,3-dioxol-2-one is an important reagent in the preparation of angiotensin II receptor antagonist such as Olmesratan Medoxomil. 4-Chloromethyl-5-methyl-1,3-dioxol-2-one is also used in the preparation of prodrugs of ampicillin.

  • Features & Specification

    PRODUCT   NAME

    4-Cloromethyl-5-methyl-1,3-dioxol-2-one

    CAS   No.:

    80841-78-7

    Synonyms

    DMDO-CL;

    4-chloromethyl-5-methyl-2-oxo-1,3-dioxolene;

    Formula:

    C5H5ClO3

    Molecular   Weight:

    148.54400

    PSA:

    43.35000

    LogP:

    1.28000

     

    Structure

          image.png           

     

    Description

    Appearance   & Physical State:

    Pale   yellow transparent liquid

    Density:

    1.362   g/cm3

    Boiling   Point:

    163.2ºC   at 760 mmHg

    Flash   Point:

    66.7ºC

    Refractive   Index:

    1.481

    Safety   Statements:

    S26

    HS   Code:

    2932999099

    Risk   Statements:

    R22

    Hazard   Codes:

    Xn

     

    Certificate of Analysis

     

    ProductName: 4-Cloromethyl-5-methyl-1,3-dioxol-2-one

    Cas:        80841-78-7

    Batch No.:     20110728

    MFG Date:  July.28.2011

    Analysis Date: July.28.2011

     

    Inspect   Item

    Quantity   Standard

    Inspection   Result

    Appearance  

    A   pale yellow transparent liquid

    Conforms

    Assay(HPLC)

    ≥97%

    97.25%

    Water

    ≤0.5%

    0.12%

    Conclusion  

    In   accordance with enterprise standard


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