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4'-Benzyloxy-2-bromopropiophenone

4'-(Benzyloxy)-2-bromopropiophenone is an intermediate in the preparation of Bazedoxifene acetate.

  • Features & Specification

    PRODUCT   NAME

    4'-Benzyloxy-2-bromopropiophenone

    CAS   No.:

    35081-45-9

    Synonyms

    4'-(Benzyloxy)-2-bromopropiophenone

    2-bromo-1-(4-phenylmethoxyphenyl)propan-1-one;

    Formula:

    C16H15BrO2

    Molecular   Weight:

    319.19300

    PSA:

    26.30000

    LogP:

    4.23170

     

    Structure

    image.png                 

     

    Description

    Density:

    1.354g/cm3

    Boiling   Point:

    424.6ºC   at 760mmHg

    Flash   Point:

    210.6ºC

    Refractive   Index:

    1.591

    HS   Code:

    2914700090

     

    Certificate of Analysis

     

    ProductName: 4'-Benzyloxy-2-bromopropiophenone

    Cas:        35081-45-9

    Batch No.:     20130401

    MFG Date:  Apr.01.2013

    Analysis Date:Apr.01.2013

     

    Inspect   Item

    Quantity   Standard

    Inspection   Result

    Appearance

    Almost   white crystalline powder

    Conforms  

    Identification

    (1)IR

    (2)   Retention time (HPLC)

    Conforms

    Loss   on drying

    ≤0.5%

    0.03%

    Melting   point

    78   ~ 81 °C

    79.8~80.1°C

    Related   Substances

    4’-Benzyloxypropiophenone≤2.0%

    0.02%

    Max   other impurity≤2.0%

    0.2%

    Sum   of impurities≤3.0%

    0.4%

    Assay

    ≥98.0%

    99.6%

    Conclusion  

    In   accordance with enterprise standard


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