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2-n-butyl-1,3-diaza-spiro[4,4]non-1-en-4-one Hydrochloride

2-Butyl-1,3-diazaspiro[4.4]non-1-en-4-one is an intermediate of Irbesartan (Avapro).

  • Features & Specification

    PRODUCT   NAME

    2-n-butyl-1,3-diaza-spiro[4,4]non-1-en-4-one   hydrochloride

    CAS   No.:

    151257-01-1

    Synonyms

    2-Butyl-1,3-diazaspiro[4.4]non-1-en-4-one   hydrochloride;

    2-BUTYL-1,3-DIAZASPIRO(4.4)NON-1-EN-4-ONE   HYDROCHLORIDE;

    Formula:

    C11H19ClN2O

    Molecular   Weight:

    230.73400

    PSA:

    41.46000

    LogP:

    2.58410

     

    Structure

    image.png       

     

    Description

    Appearance   & Physical State:

    white   or pale white crystal powder

    Boiling   Point:

    328.6ºC   at 760mmHg

    Flash   Point:

    152.6ºC

    Vapor   Pressure:

    0.000135mmHg   at 25°C

    HS   Code:

    2933990090

     

    Certificate of Analysis

     

    Product Name:2-n-butyl-1,3-diaza-spiro[4,4]non-1-en-4-one hydrochloride

    Cas: 151257-01-1

    Batch No.: 20101015

    MFG Date: Otc.15.2010

    Analysis Date: Otc.15.2010

     

    Inspect   Item

    Quantity   Standard

    Inspection   Result

    Appearance

    White   or off-white crystal

    White   or off-white crystal

    Purity(HPLC)

    98%min

    99.21%

    Related   Impurities(HPLC)

    Total   impurities NMT1.0%

    0.79%

    Individual   impurities NMTO0.5%

    0.23%

    Loss   on drying

    1.0%max

    0.57%

    Solubility

    Soluble   in methanol and water

    complies

    Conclusion

    Up   to enterprise grade


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