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Osimertinib CAS No.:1421373-66-1 Made By Hangzhou Shitai Biotech Co.,LTD In China
Mar 09, 2018

PRODUCT   NAME

Osimertinib

CAS   No.:

1421373-66-1

Synonyms

N-[2-[[2-(Dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-2-propenamide   methanesulfonate;

AZD-9291   (Mesylate)

Formula:

C28H33N7O2.CH4O3S

Molecular   Weight:

595.71

PSA:

153.79000

LogP:

5.81710

 

Structure

Description

We can provide this product with purity 99.5%.

Osimertinib CAS1421373-66-1, a new Hangzhou inhibitor for the treatment of skin cancer, is developed by Ltd Shitai Biotech Co.. The huge problem that has been plaguing patients and their families is the expensive treatment, especially the drugs used to treat cancer, which are basically monopolized by large companies. The therapeutic effect of the drug can not be directly proportional to the cost. A large amount of money is usually spent in exchange for 3-5 years of life. Our company has passed the demonstration of R & D and production process. It has been verified that the cost of the product is relatively low. But as a drug, we have to go through the preparation of the GMP production and the DMF file. This requires long - term cooperation with large companies. The treatment of the disease in the future still needs the common concern and cooperation between the government and the society. The good medicine can be more quickly and directly from the production enterprise to the patient's circulation.


Certificate of Analysis

 

 

ProductName: Osimertinib Mesylate

Cas:        1421373-66-1

Batch No.:    20170816

MFG Date:  Aug.16.2017

Analysis Date: Aug.16.2017

 

 

Inspect Item

Quantity Standard

Inspection Result

Appearance

Off-white or   yellow powder

Yellow powder

H-NMR   identification

Matches with the standards

Conforms

Crystal form

B

Conforms

Particle size

≤45um

9.41um

Ignition residue

≤0.2%

0.10%

Purity

99%Min

99.86%

Single impurity

≤0.1%

0.04%

Total impurity

≤0.5%

0.14%

Assay

98-102%

99.69%

Residue solvents

Acetone NMT 0.5%

0.41%

Water

         1.0% Max

0.10%

Heavy metal

20ppm Max

1.12ppm

Conclusion

In accordance   with enterprise standard


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