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Osimertinib

Structure : Description : We can provide this product with purity 99.5%.

  • Features & Specification

    PRODUCT NAME

    Osimertinib

    CAS No.:

    1421373-66-1


    Synonyms

    N-[2-[[2-(Dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-2-propenamide methanesulfonate;

    AZD-9291 (Mesylate)

    Formula

    C28H33N7O2.CH4O3S

    Molecular Weight

    595.71

    PSA:

    153.79000

    LogP:

    5.81710

    Structure

    图片6.png

    Description: 

    We can provide this product with purity 99.5%.



    Certificate of Analysis

    ProductName: Osimertinib Mesylate

    Cas:        1421373-66-1

    Batch No.:    20170816

    MFG Date:  Aug.16.2017

    Analysis Date: Aug.16.2017

     

     

    Inspect Item

    Quantity Standard

    Inspection Result

    Appearance

    Off-white or   yellow powder

    Yellow powder

    H-NMR   identification

    Matches with the standards

    Conforms

    Crystal form

    B

    Conforms

    Particle size

    ≤45um

    9.41um

    Ignition residue

    ≤0.2%

    0.10%

    Purity

    99%Min

    99.86%

    Single impurity

    ≤0.1%

    0.04%

    Total impurity

    ≤0.5%

    0.14%

    Assay

    98-102%

    99.69%

    Residue solvents

    Acetone NMT 0.5%

    0.41%

    Water

             1.0% Max

    0.10%

    Heavy metal

    20ppm Max

    1.12ppm

    Conclusion

    In accordance   with enterprise standard


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