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Apabetalone

Description RVX 208 (RVX-208) is an orally available small molecule created by Resverlogix Corp. that is being evaluated in clinical trials for the treatment of atherosclerosis and associated cardiovascular disease (CVD). In two phase II clinical trials in patients with established CVD, RVX-208...

  • Features & Specification

    PRODUCT NAME

    Apabetalone

    CAS No.:

    1044870-39-4



    Synonyms

    2-[4-(2-hydroxyethoxy)-3,5-dimethylphenyl]-5,7-dimethoxy-1H-quinazolin-4-one

    RVX-208

    RVX 000222

    Formula

    C20H22N2O5

    Molecular Weight

    370.39900

    PSA:

    93.67000

    LogP:

    2.59520

    Structure:

    图片3.png

    Description 

    RVX 208 (RVX-208) is an orally available small molecule created by Resverlogix Corp. that is being evaluated in clinical trials for the treatment of atherosclerosis and associated cardiovascular disease (CVD). In two phase II clinical trials in patients with established CVD, RVX-208 increased HDL-cholesterol (HDL-c) and apolipoprotein A-I (ApoA-I) levels, as well as decreased the incidence of major adverse cardiac events (MACE). Reduction of MACE was accentuated in patients with diabetes mellitus.

    Test result:

    We can provide this product with purity 98%.

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